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METHODS OF PROMOTING LONG-TERM SURVIVAL OF PATIENTS WITH ADVANCED CHEMOTHERAPY-RESISTANT MALIGNANCIES
METHODS OF PROMOTING LONG-TERM SURVIVAL OF PATIENTS WITH ADVANCED CHEMOTHERAPY-RESISTANT MALIGNANCIES
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机译:提高晚期化疗耐药恶性肿瘤患者长期生存率的方法
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摘要
Disclosed are methods for treating an individual with a chemotherapy-resistant primary and/or secondary malignancy that comprise administering a therapeutically effective amount of a tumor-targeted retrovector encoding a cytocidal dominant-negative Cyclin G1 construct, such as DeltaRex-G, to the individual. Also disclosed are methods in which DeltaRex-G, either alone or in conjunction with other cancer therapies and/or treatments, may be administered to ameliorate or eliminate the life-threatening effects of metastatic cancer.
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