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CHIMERIC LYSOZYME VARIANT AND APPLICATION THEREOF IN ANIMAL FEED ADDITIVE

机译:嵌合溶菌酶变体及其在动物饲料添加剂中的应用

摘要

Provided are a chimeric lysozyme variant having improved heat resistance and a polynucleotide encoding the variant. A novel chimeric lysozyme sequence is constructed, and high-efficiency expression in a host cell is achieved. The thermal stability of the chimeric lysozyme under the condition of 60°C is nearly doubled compared to a parental sequence. Also provided is a use of the chimeric lysozyme variant. Also provided are an animal feed additive containing the chimeric lysozyme variant and an animal feed containing the animal feed additive. The feed additive has a significant effect on animal growth performance and greatly improves the conversion rate of the feed.
机译:本发明提供了一种具有改进耐热性的嵌合溶菌酶变体和编码该变体的多核苷酸。构建了一种新的嵌合溶菌酶序列,并在宿主细胞中实现了高效表达。嵌合溶菌酶在60°C条件下的热稳定性几乎是亲本序列的两倍。还提供了嵌合溶菌酶变体的用途。还提供了包含嵌合溶菌酶变体的动物饲料添加剂和包含动物饲料添加剂的动物饲料。饲料添加剂对动物生长性能有显著影响,并大大提高饲料的转化率。

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