首页> 外国专利> METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS

METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS

机译：从植物细胞培养物中制备包含3-O-p-香豆酰基托麦酸酯的组合物的方法，其作为治疗锥虫病的抗寄生虫剂的应用

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摘要

The present invention relates to a method for the production of a (poly)hydroxylated pentacyclic triterpene composition including a 3-O-p-coumaroyl ester of tormentic acid from a plant suspension cell culture, to a pharmaceutical composition comprising at least 3-O-p-coumaroyl ester of tormentic acid for a use in the prevention and/or the treatment of trypanosomiasis, optionally in admixture with other (poly)hydroxylated pentacyclic triterpenes, and to 3-O-p-coumaroyl ester of tormentic acid for its use as an antiparasitic agent for the prevention and/or the treatment of trypanosomiasis, optionally in admixture with other (poly)hydroxylated pentacyclic triterpenes.

机译：本发明涉及一种从植物悬浮细胞培养物中生产（聚）羟基化五环三萜组合物的方法，该组合物包括托麦特酸的3-O-p-香豆酰基酯，以及一种包含托麦特酸的至少3-O-p-香豆酰基酯的药物组合物，用于预防和/或治疗锥虫病，任选与其他（聚）羟基化五环三萜混合，并任选与其他（聚）羟基化五环三萜混合，并任选与用作预防和/或治疗锥虫病的抗寄生虫剂的3-O-p-香豆酰基托麦酯混合。

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公开/公告号US2022151970A1

专利类型
公开/公告日2022-05-19

原文格式PDF
申请/专利权人 LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY;UNIVERSITÉ CATHOLIQUE DE LOUVAIN;
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申请/专利号US202017428369
发明设计人 CHRISTELLE ANDRE;JOELLE LECLERCQ;CLAIRE BEAUFAY;LUCY CATTEAU;SYLVAIN LEGAY;
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申请日2020-02-06
分类号A61K31/215;A61K31/19;A61P33/02;C12P15;
国家 US
入库时间 2022-08-25 01:07:06

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