Combination Therapy of Donepezil and sildenafil for the Treatment of Alzheimer's Disease or Cognitive Impairment

摘要

The present invention relates to donepezil and sildenafil combination therapy for the prevention, treatment or amelioration of Alzheimer's disease or cognitive dysfunction. Since the combined administration of donepezil and sildenafil according to the present invention has a superior effect on improving Alzheimer's disease or cognitive dysfunction compared to donepezil alone, it can be usefully used as a treatment regimen for Alzheimer's disease or cognitive dysfunction or as a combination agent.