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METHODS AND COMPOSITIONS FOR TREATING EPSTEIN BARR VIRUS-ASSOCIATED CANCER

机译:治疗EB病毒相关癌症的方法和组合物

摘要

This disclosure describes a novel "kick and kill" strategy as an effective cancer therapy for treating virus-associated cancers. In particular, this disclosure provides a method of reactivating a latent Epstein-Barr virus (EBV) in a cell infected with the EBV. Also provided are a method of eliciting or enhancing an immune response against an EBV-positive cancer cell in a subject infected with the EBV and a method of treating a subject having cancer associated with EBV infection.
机译:本发明描述了一种新的“踢杀”策略,作为治疗病毒相关癌症的有效癌症疗法。具体而言,本发明提供了一种在感染EB病毒的细胞中重新激活潜在EB病毒(EBV)的方法。还提供了一种在感染EBV的受试者中激发或增强针对EBV阳性癌细胞的免疫应答的方法以及治疗患有与EBV感染相关的癌症的受试者的方法。

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