首页> 外国专利> Composition for preventing, improving, or treating inflammation comprising peptides derived From Haliotis Discus as effective component

Composition for preventing, improving, or treating inflammation comprising peptides derived From Haliotis Discus as effective component

机译:包含从皱纹盘鲍中提取的肽作为有效成分的用于预防、改善或治疗炎症的组合物

摘要

The present invention relates to a composition for preventing, improving or treating inflammation comprising a peptide derived from abalone as an active ingredient. Specifically, it relates to a cosmetic composition, a composition for external application for skin, a health functional food composition, a food additive and a pharmaceutical composition having the efficacy of preventing, improving or treating inflammation by including a peptide derived from abalone as an active ingredient. Since the abalone-derived peptide according to the present invention is small in size, it has excellent skin penetration rate, and nitric oxide (NO), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (Cyclooxygenase) -2: COX-2), TNF-α (tumor necrosis factor-α), IL-1β (interleukin-1β), and IL-6 (interleukin-6) through the expression inhibitory activity of an inflammatory activator selected from It has an excellent inflammatory effect and can replace conventional anti-inflammatory drugs. The peptide may be utilized in products such as a quasi-drug composition, a health functional food composition, and a pharmaceutical composition as well as a cosmetic composition for anti-inflammatory.
机译:本发明涉及一种用于预防、改善或治疗炎症的组合物,其包含从鲍鱼中提取的肽作为活性成分。具体而言,本发明涉及一种化妆品组合物、皮肤外用组合物、保健功能性食品组合物、食品添加剂和药物组合物,其具有通过包括从鲍鱼中提取的肽作为活性成分来预防、改善或治疗炎症的功效。由于根据本发明的鲍鱼衍生肽体积小,因此其具有优异的皮肤穿透率,以及一氧化氮(NO)、诱导型一氧化氮合酶(iNOS)、环氧合酶-2(环氧合酶)-2:COX-2、TNF-α(肿瘤坏死因子-α)、白细胞介素-1β(白细胞介素-1β),而IL-6(白细胞介素-6)通过表达抑制活性从中选择一种炎症激活剂,具有极好的炎症作用,可以替代传统的抗炎药。该肽可用于诸如准药物组合物、保健功能性食品组合物、药物组合物以及用于抗炎的化妆品组合物等产品中。

著录项

  • 公开/公告号KR102385070B1

    专利类型

  • 公开/公告日2022-04-12

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20200079228

  • 申请日2020-06-29

  • 分类号A61K8/64;A23L33/18;A61K35/618;A61K38/08;A61K8/98;A61K9;A61P29;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-25 00:37:44

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