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INDUCTION BY LOW DOSE RADIATION OF CANCER CELL TARGETS FOR CELL-BASED OR SMALL MOLECULE THERAPY
INDUCTION BY LOW DOSE RADIATION OF CANCER CELL TARGETS FOR CELL-BASED OR SMALL MOLECULE THERAPY
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机译:低剂量辐射诱导癌细胞靶点用于细胞或小分子治疗
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摘要
We disclose a method, comprising administering, to a patient suffering from a cancer, low-dose radiation, whereby expression of a target on a surface of a cancer cell increases after the low-dose radiotherapy; and administering, to the patient, a cell-based target-specific cancer therapy, wherein a cell of the cancer therapy interacts with the target. The method may further comprise administering an additional cancer treatment modality. We also disclose a kit comprising a cell of the cell-based target-specific cancer therapy; and instructions to perform the method. Further, we disclose a similar method and corresponding kit, wherein low-dose radiation induces expression of an intracellular target, and a small molecule cancer therapy interacting with the intracellular target is administered.
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