METHOD FOR DETECTING CONTENT OF 6-OXOSIMVASTATIN IN EZETIMIBE-SIMVASTATIN TABLETS

摘要

Disclosed is a method for detecting the content of 6-oxosimvastatin in Ezetimibe-Simvastatin tablets, which uses high performance liquid chromatography for detection. The present invention may not only quantitatively determine the content of 6-oxosimvastatin in Ezetimibe-Simvastatin tablets, but also completely separate 6-oxosimvastatin from impurities, and has a good peak shape, thus meeting the requirements of Chinese Pharmacopoeia. Moreover, the method has a low detection limit, effectively controls the quality of raw materials in Ezetimibe-Simvastatin tablets, has strong specificity, a high degree of separation, high sensitivity and good accuracy.