Viniferin derivatives, preparation method thereof and composition for preventing or treating infection caused by pneumococcal biofilm comprising the same as an active ingredient

摘要

The present invention relates to a viniferin derivative compound represented by the following [Formula 1] to [Formula 4], a preparation method thereof, and a composition for preventing or treating infections caused by pneumococcal biofilm comprising the same as an active ingredient, pneumococcus ( Streptococcus pneumoniae) relates to an antibacterial composition and a coating composition for inhibiting the formation of a pneumococcal biofilm. [Formula 1] [Formula 2] [Formula 3] [Formula 4] The pharmaceutical composition, antibacterial composition and coating composition of the present invention have excellent antibacterial effects, and in particular, have antibacterial and antibiotic activity effects against Streptococcus pneumoniae. In addition, it exhibits excellent efficacy in inhibiting pneumococcal biofilm formation and removing already formed biofilm, preventing or treating various infections caused by biofilm, and biofilm formed in various medical devices, medical materials, or medical implants. It can be usefully used in a composition for coating to suppress