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A humanized antibody to Digoxigenin and use thereof

机译:一种地高辛人源化抗体及其用途

摘要

The present disclosure relates to a humanized antibody having excellent binding affinity to digoxigenin and uses thereof. When the antibody or antigen-binding fragment thereof specifically recognizing digoxigenin according to one aspect of the present disclosure is used, the concentration of the drug in the human body is adjusted as necessary through the complex (DOligobody) comprising the same, or the drug is administered in vivo. It is expected to increase the half-life.
机译:本发明涉及一种与地高辛有极好结合亲和力的人源化抗体及其用途。当使用根据本发明一个方面的特异性识别地高辛的抗体或其抗原结合片段时,根据需要通过包含该抗体或抗原结合片段的复合物(DOligobody)调节药物在人体中的浓度,或在体内投与药物。预计会增加半衰期。

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