Anti-PD-1 / anti-HER2 natural antibody structural form heterodimeric bispecific antibody and method for producing the same.

摘要

The present invention relates to an anti-PD-1 / anti-HER2 natural antibody structural form heterodimeric bispecific antibody and a method for producing the same. Specifically, a highly stable heterodimeric anti-PD-1 / anti-HER2 bispecific antibody, which has properties of natural IgG and has no mismatch between heavy and light chains, and A method for producing the same is provided, and the bispecific antibody can bind to two target molecules at the same time, and exhibits a further excellent effect in treating a complex disease.