Magnesium-containing oxytocin preparation and method of use

摘要

Disclosed is a magnesium-containing oxytocin peptide formulation or composition comprising an oxytocin peptide and a magnesium salt that results in synergistic analgesia when used in the treatment of pain. Also disclosed is a method for treating pain (eg, migraine) comprising co-administration of an oxytocin peptide and a magnesium salt. The oxytocin peptide can also be administered before or after administration of the magnesium salt. The oxytocin peptide can be administered via intranasal administration.