PHOSPHOLIPID THREE-DIMENSIONAL VESICULAR AGGREGATES SCATTERED IN ALCOHOLIC MIXTURES WITH NO OR LOW WATER CONTENT, THEIR PREPARATION AND USE IN FORMULATIONS FOR TOPICAL APPLICATION

摘要

The present invention relates to three-dimensionally aggregated vesicles formed by phospholipid molecules and at least one pharmacologically and/or cosmetically active principle, preferably water-insoluble, but also water-soluble, which are dispersed in a carrier substantially consisting of mixtures having a different composition of alcohols, polyalcohols and/or polyoxyethylenes, in the presence or absence of water (from 0 to 25% v/v of the dispersing carrier; preferably 0 to <25% v/v). The invention also relates to the preparation of said three-dimensionally aggregated phospholipid-based vesicles and to the use thereof in topical compositions for carrying said pharmaceutical and/or cosmetic active substances.