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IMMUNE MECHANISM AND THERAPEUTIC DRUG FOR BILIARY ATRESIA

机译:胆道闭锁的免疫机制及治疗药物

摘要

A drug and a method for preventing/treating biliary atresia, the method comprising administering a drug for removing B cells to a subject, wherein the drug for removing B cells is selected from a CD20 inhibitor, a B cell maturation antigen inhibitor, and a CD79 inhibitor. The CD20 inhibitor is selected from rituximab, ibritumomab, tositumomab or an analog thereof, and has a certain significance for the clinical treatment of biliary atresia.
机译:一种用于预防/治疗胆道闭锁的药物和方法,该方法包括向受试者投与用于移除B细胞的药物,其中用于移除B细胞的药物选自CD20抑制剂、B细胞成熟抗原抑制剂和CD79抑制剂。CD20抑制剂选自利妥昔单抗、伊布单抗、托西单抗或其类似物,对胆道闭锁的临床治疗具有一定意义。

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