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Solid dispersion

机译:扎实的分散

摘要

The present invention relates to a solid dispersion containing a compound represented by General Formula (I):; wherein R1 is an unsubstituted phenyl group or a phenyl group substituted with a substituent; the substituent is an alkyl group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms substituted with a halogen atom, an alkoxy group having 1 to 8 carbon atoms, an alkoxycarbonyl group having 2 to 8 carbon atoms, a formyl group, a carboxyl group, a halogen atom, a phenyl group or a phenoxy group; R2 is a cyano group or a nitro group; R3 is a hydroxyl group; X is an oxygen atom or —S(O)n—; n is an integer of 0 to 2; Y is an oxygen atom or a sulfur atom, or a pharmaceutically acceptable salt thereof and a hypromellose derivative.
机译:本发明涉及含有通式(I)表示的化合物的固体分散体: 其中R1是未取代的苯基或被取代基取代的苯基; 取代基是具有1至8个碳原子的烷基,其具有1至8个碳原子被卤原子取代的烷基,具有1至8个碳原子的烷氧基,具有2至8个碳原子的烷氧基羰基,甲醛基 组,羧基,卤素原子,苯基或苯氧基; R2是氰基或硝基组; R3是羟基; X是氧原子或-s(o)n-; n是0到2的整数; Y是氧原子或硫原子,或其药学上可接受的盐和杂毛铅衍生物。

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