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POLYPEPTIDE WITH ENHANCED RATE OF SPONTANEOUS ISOPEPTIDE BOND FORMATION WITH ITS PEPTIDE TAG PARTNER AND USES THEREOF
POLYPEPTIDE WITH ENHANCED RATE OF SPONTANEOUS ISOPEPTIDE BOND FORMATION WITH ITS PEPTIDE TAG PARTNER AND USES THEREOF
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机译:具有增强的自发性异肽键形成率的多肽,其肽标签伴侣及其用途
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摘要
The present invention relates to a polypeptide that forms one part of a two- part linker in which the polypeptide spontaneously forms an isopeptide bond with a peptide tag, the second part of the two-part linker. Nucleic acid molecules encoding the polypeptide, vectors comprising said nucleic acid molecules,and host cells comprising said vectors and nucleic acid molecules are also provided. A kit comprising said two-part linker (i.e. peptide tag and polypeptide binding partner), and/or nucleic acid molecules/vectors is also provided. A method of producing the polypeptide (binding partner) and the uses of the polypeptide of the invention are also provided.
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