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HIGH AVIDITY WT1 T CELL RECEPTORS AND USES THEREOF
HIGH AVIDITY WT1 T CELL RECEPTORS AND USES THEREOF
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机译:高厌恶WT1 T细胞受体及其用途
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摘要
The present disclosure provides T cell receptors (TCRs) and related binding proteins with high functional avidity against tumor associated antigen p37 from Wilms tumor protein 1 (WT1), T cells expressing such high affinity WT1 specific TCRs, nucleic acids encoding the same, and compositions for use in treating diseases or disorders in which cells overexpress WT1 and/or produce the p37 antigen, such as in cancer.
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