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LACTOBACILLUS PLANTARUM STRAIN KBL396 AND APPLICATION THEREOF

机译:Lactobacillus plantarum菌株Kbl396及其应用

摘要

FIELD: biotechnology.;SUBSTANCE: group of inventions relates to a strain intended for increasing serotonin secretion, a pharmaceutical composition, a food composition, an additive to animal feed, and a method for preventing or treating neurological diseases. Proposed is a Lactobacillus plantarum strain KBL396 (KCTC13278BP) for increasing serotonin secretion. Also proposed are pharmaceutical compositions containing said strain or culture thereof and used to increase serotonin secretion or to prevent or treat neurological diseases. Also proposed are a food composition, an additive to animal feed, a composition intended for producing a preventive or therapeutic medicinal product for preventing or treating neurological diseases containing said strain or culture thereof. Also proposed is a method for preventing of treating neurological diseases, including administration of a therapeutically effective amount of said strain or culture thereof to a subject in need thereof.;EFFECT: group of inventions improves the cognitive ability, the ability for recovery after stress, and improves the state of depression when using the Lactobacillus plantarum strain KBL396 (KCTC13278BP) capable of increasing serotonin secretion.;15 cl, 9 dwg, 4 tbl, 10 ex
机译:现场:生物技术。物质:发明组涉及用于增加血清素分泌,药物组合物,食品组合物,动物饲料添加剂的菌株,以及用于预防或治疗神经疾病的方法。提出是一种用于增加血清素分泌的乳酸杆菌菌株KBL396(KCTC13278BP)。还提出了含有所述菌株或其培养物的药物组合物,并用于增加血清素分泌或预防或治疗神经疾病。还提出的是食品组合物,对动物饲料的添加剂,一种用于生产预防或治疗药物的组合物,用于预防或治疗含有所述菌株或其培养的神经疾病。还提出了防止治疗神经疾病的方法,包括将治疗有效量的所述菌株或其培养物施用于有此需要的受试者。;效果:发明组提高了认知能力,压力后恢复能力,使用能够增加血清素分泌的乳酸杆菌菌株KBL396(KCTC13278BP)时改善抑郁状态。; 15CL,9 DWG,4 TBL,10例

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