Composition for preventing or treating renal disease comprising Zizyphus jujuba MILL extract

摘要

A pharmaceutical composition for preventing or treating kidney disease, a food composition for preventing or improving kidney disease, a quasi-drug composition, a method for producing a jujube root extract or a fraction thereof, comprising a compound isolated from the jujube root extract as an active ingredient and methods of preventing or treating kidney disease in a subject. The composition of the jujube tree ( Zizyphus jujuba MILL.) root extract according to an aspect can inhibit renal cell death from renal cell-damaging substances, and by using the extract, it can be effectively used for the prevention, improvement or treatment of kidney disease, When the extract is included as an active material, it can be used as a pharmaceutical composition or a food composition. In addition, since the active ingredient of the 3-dihydroxyceanothetric acid 2-methyl ester compound contained in the fraction of the extract also exhibits renal cell protective activity, including the compound as a pharmaceutical material or health functional It can be effectively used as a food material.