Gene delivery system comprising triple-coated nanoparticles and EGRF-CAR gene with a specific domain structure

摘要

It relates to nanoparticles and NK cells for immunotherapy and pharmaceutical compositions comprising the same, and according to the nanoparticles according to an aspect, it is possible to express genes by delivering genes to immune cells, and to NK cells into which the nanoparticles are introduced. According to the report, it effectively treats cancer without the side effects of existing CAR T cells and at the same time has the effect of tracking cells.