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Analyzing Complex Single Molecule Emission Patterns with Deep Learning
Analyzing Complex Single Molecule Emission Patterns with Deep Learning
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机译:深入学习分析复杂的单分子发射模式
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摘要
A fluorescent single molecule emitter simultaneously transmits its identity, location, and cellular context through its emission patterns. A deep neural network (DNN) performs multiplexed single-molecule analysis to enable retrieving such information with high accuracy. The DNN can extract three-dimensional molecule location, orientation, and wavefront distortion with precision approaching the theoretical limit of information content of the image which will allow multiplexed measurements through the emission patterns of a single molecule.
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