SEQUENTIAL ACTIVATION OF ELECTRODE-PAIRS DURING IRREVERSIBLE ELECTROPORATION (IRE)

摘要

An irreversible electroporation (IRE) method includes placing multiple electrodes of a catheter in contact with tissue of an organ. Bipolar IRE pulses are generated. The tissue is ablated by applying the bipolar IRE pulses to pairs of the electrodes, in accordance with an order in which successive activations of a given electrode-pair are interleaved with activation of at least one other electrode-pair, and are spaced in time by at least a predefined duration.