Heparan sulfate with a high 3-O-sulfation rate of glucosamine residues

摘要

PROBLEM TO BE SOLVED: To provide a novel sulfated polysaccharide having anticoagulant activity. SOLUTION: It contains a repeating structure of a disaccharide unit consisting of a hexuronic acid (HexA) residue and an α-D-glucosamine (GlcN) residue, and the 3-O-sulfation rate of the GlcN residue is 13% or more. , Provides polysaccharides. [Selection diagram] None