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IMAGING SURFACE PLASMON RESONANCE APPARATUS

机译:成像表面等离子体共振装置

摘要

An imaging surface plasmon resonance apparatus comprises: a prism; a two dimensional vertical-cavity surface-emitting laser array; a layer of metal; and a detector. The two dimensional vertical-cavity surface-emitting laser array is operable to produce a two dimensional array of beams of electromagnetic radiation and is arranged such that each one of said two dimensional array of beams of electromagnetic radiation is coupled into the prism and is incident on a different one of a plurality of regions on a surface of the prism. The beams of electromagnetic radiation in the two dimensional array of beams of electromagnetic radiation may be generally mutually parallel. The layer of metal is disposed on or adjacent to the surface of the prism in the vicinity of each of the plurality of regions on the surface of the prism. The layer of metal may comprise a two dimensional array of receptor sites for supporting a receptor, each receptor site disposed on a surface of the layer of metal that is distal to the prism and adjacent one of the plurality of regions on the surface of the prism. The detector is arranged to receive a portion of each of the plurality of beams of electromagnetic radiation which is reflected from the interface between the prism and the layer of metal and operable to determine an intensity of said portion of each of the plurality of beams of electromagnetic radiation.
机译:成像表面等离子体共振装置包括:棱镜;二维垂直腔表面发射激光阵列;一层金属;和一个探测器。两个尺寸垂直腔表面发射激光器阵列可操作以产生两维的电磁辐射束阵列,并且布置成使得所述电磁辐射的两个尺寸束中的每一个串联耦合到棱镜中并入射在棱镜的表面上的多个区域中的不同之一。电磁辐射束中的二维阵列中的电磁辐射束可以通常是相互平行的。金属层设置在棱镜表面上的每个区域中的每一个附近的棱镜的表面上或附近。金属层可包括用于支撑受体的两维受体位点阵列,每个受体位点设置在金属层的表面上,其与棱镜远侧并且在棱镜表面上的多个区域中的一个相邻。检测器被布置成接收来自棱镜和金属层之间的界面的多个电磁辐射中的每一个的一部分,并且可操作以确定多个电磁梁中的每一个的所述部分的强度辐射。

著录项

  • 公开/公告号WO2022002991A1

    专利类型

  • 公开/公告日2022-01-06

    原文格式PDF

  • 申请/专利权人 AMS INTERNATIONAL AG;

    申请/专利号WO2021EP67933

  • 发明设计人 VERDOOLD REMCO;LOUS ERIK JAN;

    申请日2021-06-30

  • 分类号G01N21/552;G01N21/25;G01N33/543;

  • 国家 EP

  • 入库时间 2024-06-14 22:40:32

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