METHODS FOR PREDICTING THE RISK OF LOCAL INVASION AND/OR METASTASIS INDUCED BY AN ANTIANGIOGENIC TREATMENT

摘要

The present invention relates to methods useful for predicting the risk of local invasion and/or metastasis induced by an antiangiogenic treatment in a patient who suffers from cancer, or for predicting the response to an antiangiogenic therapy, wherein the methods comprise the determination of the expression level of ALDH1A3, as well as methods for providing personalized medicine to said patients. These methods can be used to identify those patients who are at a high risk of local invasion and/or metastasis. The identification of this subgroup of patients may guide the selection of therapies, improving financial and health outcomes. The invention relates as well to the use of reagents for carrying out the predictive methods.