A randomized peptide library presented by human leukocyte antigens

摘要

In this specificationAn antigen screening library comprising multiple human leukocyte antigens (HLA) - antigen polypeptide complexesHLA - antigen polypeptide complexHLA polypeptide(b) contains an amino acid sequence shown in any one of sequence numbersA randomized antigen polypeptide selected to bind specifically to peptide binding grooves of HLA polypeptides(c) β An antigen screening library containing 2 - microglobulin polypeptides is described.These libraries can be used to determine antigen polypeptides that interact with the selected T cell receptor (TCR) to stimulate it.Diagram