首页> 外国专利> 1-isopropyl-3-methyl-8 - (pyridin-2-yl) - 1,3-dihydro-2h-imidazo 4,5-c cinolin-2-one and its use as a selective modulator of telangiectasia (ATM) kinase

1-isopropyl-3-methyl-8 - (pyridin-2-yl) - 1,3-dihydro-2h-imidazo 4,5-c cinolin-2-one and its use as a selective modulator of telangiectasia (ATM) kinase

机译:1-异丙基-3-甲基-8-(吡啶-2-基) - 1,3-二氢-2H-咪唑[4,5-C]鳞蛋白-2-α-1及其用作Telanciectasia的选择性调节剂(ATM )激酶

摘要

The present invention relates to a novel substituted imidazo [4,5-c] cinolin-2-one compound and a pharmaceutically acceptable salt thereof that selectively regulates a capillary vasodiastolic mutation ("ATM") kinase.The present application also relates to the pharmaceutical composition comprising one or more of the compounds and their salts as active components, and the use of the compounds and their salts in the treatment of ATM related diseases or symptoms involving cancer.No selection
机译:本发明涉及一种新型取代的咪唑[4,5-C]肉蛋白-2-一种化合物及其药学上可接受的盐,其选择性地调节毛细管血管突变突变(“ATM”)激酶。本申请还涉及药物 组合物包含一种或多种化合物及其盐作为活性成分,以及化合物及其盐在治疗ATM相关疾病或涉及癌症的症状中的使用。NO选择

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