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CLOSED-LOOP PERIPHERAL NERVE STIMULATION FOR RESTORATION IN CHRONIC PAIN
CLOSED-LOOP PERIPHERAL NERVE STIMULATION FOR RESTORATION IN CHRONIC PAIN
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机译:闭环外周神经刺激以恢复慢性疼痛
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摘要
A closed-loop implantable neurostimulator system for mitigating chronic pain, the closed-loop implantable neurostimulator system including a neuromodulation device comprising one or more electrodes configured to measure a physiological signal of a subject and deliver an electrical stimulation signal to a target area in the subject and a controller, in communication with the one or more electrodes, comprising a processor and a computer- readable memory storing a trained healthy computer model, the controller configured to analyze the physiological signal that is measured using the trained healthy computer model to identify a corrective electrical stimulation signal that, when delivered by the one or more electrodes to the target area, reduces pathological neuronal events in the target area while preserving acute pain response.
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