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TREATMENT FOR AGE- AND OXIDATIVE STRESS-ASSOCIATED MUSCLE ATROPHY AND WEAKNESS

机译:治疗年龄和氧化应激相关肌肉萎缩和弱点

摘要

The present invention includes methods and compositions for treating a skeletal muscular atrophy caused by a defect in the function of one or more sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pumps comprising: identifying a subject having a muscular atrophy caused by a defect in the function of the one or more SERCA pumps, and providing the subject with an effective amount of an activator that enhances an activity of the one or more SERCA pumps.
机译:本发明包括用于治疗由一种或多种Sarco /内质网Ca2 + -AtPase(Serca)泵的功能中的缺陷引起的骨骼肌萎缩的方法和组合物,其包括:鉴定具有由缺陷引起的肌肉萎缩的受试者 一个或多个SERCA泵的功能,并提供有效量的活化剂,其增强了一个或多个SERCA泵的活性。

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