METHOD AND SYSTEM FOR MICROBIOME-DERIVED COMPANION DIAGNOSTICS

摘要

A method for characterizing compatibility of a drug for a user includes collecting a set of samples from a set of individuals comprising a set of first individuals who respond to a therapy for a microbiome-related condition and a set of second individuals who do not respond to the therapy for the microbiome-related condition and determining one or more datasets based on the set of samples. A set of microbiome features is extracted from the one or more microbiome datasets, the microbiome features facilitating differentiation between individuals who respond and individuals who do not respond to the therapy. A companion diagnostics model is determined based on the set of microbiome features. The compatibility of the drug for the user is then determined using the companion diagnostics model.