APPLICATION OF AN EZH2 INHIBITOR IN COMBINATION WITH A BTK INHIBITOR IN PRODUCTION OF A MEDICINAL PRODUCT FOR TREATING A TUMOUR

摘要

FIELD: medicine.;SUBSTANCE: invention relates to an application of a combination of an EZH2 inhibitor and a BTK inhibitor in production of a medicinal product for treating a tumour, differs in that the EZH2 inhibitor constitutes a compound by the formula (IE) or a pharmacologically acceptable salt thereof, the BTK inhibitor constitutes a compound by the formula (IIA) or a pharmacologically acceptable salt thereof, wherein the tumour is selected from the group consisting of diffuse B-large cell lymphoma and follicular lymphoma.;EFFECT: application of an EZH2 inhibitor and a BTK inhibitor in treatment of tumours.; ;7 cl, 5 dwg, 6 tbl, 4 ex