MIT biomarker and its usage

摘要

Problem to be solved: to provide a new diagnosis and treatment target of human renal cell carcinoma.Translocation or inversion of one or more genes selected from MITF, TFEB, TFE3, tfec, and / or sbno2 A diagnostic method characterized by detecting (e.g., reorganization and / or fusion), and a diagnostic method based on changes in gene expression derived from translocation of these genes, etc.Further, a treatment target such as met or brc7 indicating the rising expression and activity by the translocation or the like is provided.No selection