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HYDROPHILIC SKIRT FOR PARAVALVULAR LEAK MITIGATION AND FIT AND APPOSITION OPTIMIZATION FOR PROSTHETIC HEART VALVE IMPLANTS
HYDROPHILIC SKIRT FOR PARAVALVULAR LEAK MITIGATION AND FIT AND APPOSITION OPTIMIZATION FOR PROSTHETIC HEART VALVE IMPLANTS
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机译:用于静脉泄漏缓解和适合的静脉泄漏缓解和满分优化的亲水裙,对假肢心脏瓣膜植入物
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摘要
The present invention provides a prosthetic heart valve device with improved fit, apposition and/or paravalvular leakage mitigation. Thus, the prosthetic device comprises an anchoring structure for supporting prosthetic valve leaflets, wherein the anchoring structure comprises and/or is formed at least partially from a hydrophilic material designed to swell when contacted by the water solute in the patient's blood. Locating the hydrophilic material to provide swelling to improve the fit and/or apposition of the device to the patient's tissues results in, inter alia, improved paravalvular leakage mitigation. Some of the methods and mechanisms described herein may also be used to provide a seal against the septal hole created during transseptal delivery of the device.
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