METHOD FOR INDUCING ANTITUMOR IMMUNITY USING SINDBIS VIRAL VECTORS AND TUMOR ASSOCIATED ANTIGENS

摘要

A method for treating a mammal harboring a tumor comprising the steps of identifying a tumor associated antigen (TAA) expressed by the tumor,, and parenterally administering to the mammal a therapeutically effective amount of a Sindbis viral vector carrying a gene encoding the TAA to the mammal sufficient to elicit an immune response directed against the tumor, and thereby treating, the tumor.