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LATERAL FLOW DEVICE FOR DETECTION OF NEUTRALIZING ANTIBODIES AGAINST SARS-COV-2
LATERAL FLOW DEVICE FOR DETECTION OF NEUTRALIZING ANTIBODIES AGAINST SARS-COV-2
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机译:用于检测抗SARS-COV-2的中和抗体的侧向流动装置
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摘要
The present disclosure provides a lateral flow device, and methods of use of the device, for accurately and rapidly detecting a COVID-19 infection in a subject. The lateral flow device described herein detects in a liquid sample from the subject the presence or absence of neutralizing and non-neutralizing anti-S1 spike antibodies as IgM and IgG types. The anti-S1 antibodies neutralizing antibodies (e.g., both IgM and IgG) can block binding between ACE2 antigen and S1 spike protein which is the basis for the design of the lateral flow device.
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