WHITE DWARF: CROSS-POLARIZED WHITE LIGHT SLIDE-FREE IMAGING

摘要

The system includes: a sample holder configured to hold a stained tissue sample; an objective positioned to gather and focus light from the stained tissue sample; and a white light source that produces unpolarized white light and a polarizing beam splitter that allows one polarization direction of the white light to pass through to form an illumination beam having a first polarization direction, which is directed through the objective and onto the stained tissue sample causing the stained tissue sample to remit light that passes back through the objective and into the polarizing beam splitter. The polarizing beam splitter divides the remitted light into two orthogonally polarized remitted light beams, wherein one of the beams provides an imaging beam, which has a second polarization direction that is substantially orthogonal to the first polarization direction. Finally, the system includes an imaging device, which captures the imaging beam.