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SYNP151 (PROC29), A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN RETINAL GANGLION CELLS

机译:SYNP151(PROC29),一种用于视网膜神经节细胞中基因的特异性表达的启动子

摘要

The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 550 bp having at least 80% identity to said sequence of SEQ ID NO:1, and uses thereof, wherein said isolated nucleic acid molecule specifically leads to the expression in retinal ganglion cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
机译:本发明提供了包含的分离的核酸分子,其包含SEQ ID NO:1的核酸序列或至少550bp的核酸序列,其具有至少80%的SEQ ID NO:1的序列具有至少80%的同一性 并且其用途,其中所述分离的核酸分子在与所述基因的核酸序列可操作地连接时,该分离的核酸分子在基因的视网膜神经节细胞中产生的表达。

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