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TARGETED UBIQUITINATION DEGRADATION BRD4 PROTEIN COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

机译:靶向泛素化降解BRD4蛋白化合物,其制备方法及其应用

摘要

The present invention relates to a compound represented by formula (I) or a tautomer, optical isomer, deuterated substance, oxynitride, solvate, pharmaceutically acceptable salt or prodrug thereof, a preparation method for the compound, a pharmaceutical composition containing same and a use of the compound or the pharmaceutical composition in the preparation of a drug for the prevention and/or treatment of cancer, tumors, viral infections, depression, neurological disorders, trauma, age-related cataracts, organ transplant rejection or autoimmune diseases.
机译:本发明涉及由式(I)或互变异构体,光学异构体,氘代,掺杂物质,氧氮化物,溶剂化物,其药学上可接受的盐或前药的化合物,其用于该化合物的制备方法,含有相同和使用的药物组合物 该化合物或药物组合物在制备用于预防和/或治疗癌症,肿瘤,病毒感染,抑郁症,神经系统疾病,创伤,年龄相关性白内障,器官移植排斥或自身免疫疾病中的药物。

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