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Nitric oxide-releasing phosphodiesterase type 5 inhibitor

机译:一氧化氮释放磷酸二酯酶类型5抑制剂

摘要

Nitric Oxide-Releasing Phosphodiesterase Type 5 Inhibitor The present invention is useful in treating ocular conditions associated with elevated intraocular pressure, such as ocular hypertension, glaucoma or retinopathy, according to formula (I) or (Ib) or ( II), a nitric oxide-releasing phosphodiesterase type 5 (PDE5) inhibitor, or a steric isomer thereof or a pharmaceutically acceptable salt thereof. The present invention further relates to 3-[(2S) -2,3-bis (nitrooxy) propoxy] for use in the treatment of ocular conditions associated with elevated intraocular pressure, such as ocular hypertension, glaucoma or retinopathy. With respect to propanoic acid and 6- (nitrooxy) hexanoic acid.
机译:一氧化氮释放磷酸二酯酶型5抑制剂本发明可用于治疗与升高的眼内压力相关的眼部条件,例如MeNulary高血压,青光眼或视网膜病变,根据式(I)或(IB)或(II),一氧化氮 - 磷酸二酯酶型5(PDE5)抑制剂或其空间异构体或其药学上可接受的盐。 本发明还涉及3 - [(2S)-2,3-双(硝基氧基)丙氧基]用于治疗与升高的眼内压力相关的眼部病症,例如眼高血压,青光眼或视网膜病变。 关于丙酸和6-(硝基氧基)己酸。

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