首页>
外国专利>
Mitomycin: it can eliminate malignant stem cells (CSCs) by inhibiting mitochondrial respiration and targeting flavin containing enzymes
Mitomycin: it can eliminate malignant stem cells (CSCs) by inhibiting mitochondrial respiration and targeting flavin containing enzymes
展开▼
机译:丝裂霉素:通过抑制线粒体呼吸和靶向黄素含有酶来消除恶性干细胞(CSC)
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present disclosure relates to compounds that bind to flavin-containing enzymes and inhibit mitochondrial function, referred to herein as mitoflavoscins. Methods of screening compounds for mitochondrial inhibition and anti-cancer properties are disclosed. Also described are methods of using mitoflavoscins to prevent or treat cancer, bacterial infections, and pathogenic yeast, as well as methods of using mitoflavoscins to provide anti-aging benefits. Specific mitoflavoscin compounds are also disclosed.
展开▼