High Temperature Tolerant Salmonella Phage with Wide Dissolution Spectrum and Combinations thereof

摘要

FIELD OF THE INVENTION The present invention relates to the field of bacteriophage technology, and more particularly to high temperature resistant Salmonella phages with a wide dissolution spectrum and combinations thereof. The Salmonella phage is characterized in that the Salmonella phage SG8P3 ( Salmonella pullorum phage SG8P3). Salmonella phage SG8P3 of the present invention has excellent high temperature resistance, and the survival rate reaches 80% even after 2 hours in a 65°C water bath, and shows a titer of 10 6 PFU/mL after 2 hours in a 75°C water bath. Salmonella phage SG8P3 at a concentration of 10 2 to 10 3 cfu/mL in Salmonella medium at a concentration of 10 4 to 10 6 PFU/mL shows a wide-spectrum bactericidal power of 99% or more; The combination of Salmonella phage SG8P3 can solubilize more Salmonella with stronger solubility with a dissolution rate greater than 98%.