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Microspheres with improved drug encapsulation rate and sustained release ability and method for preparing the same

机译:微球,具有改善的药物包封率和持续释放能力和制备方法的方法

摘要

The present invention relates to microspheres having improved drug encapsulation rate and sustained release ability and a method for producing the same, and more particularly, to microspheres comprising memantine pamoate salt and made of a biocompatible polymer and a method for producing the same. it's about The microspheres containing memantine pamoate salt according to the present invention exhibit a stable drug release rate for a long period of time, so that memantine can be maintained at an effective concentration in the blood for a certain period of time, thereby extending the drug administration cycle and increasing the patient's medication compliance. , it can alleviate the side effects caused by the rapid initial release of the drug.
机译:本发明涉及具有改善的药物包封速率和持续释放能力的微球和生产方法,更具体地,更具体地,涉及包含Memantine Pamoate盐的微球,并由生物相容性聚合物制成和制造该方法。 它是关于含有根据本发明的含有Memantine酰胺盐的微球,在很长一段时间内表现出稳定的药物释放速率,使得Memantine可以在血液中的有效浓度保持一段时间,从而延长药物 管理周期并增加患者的药物遵守情况。 ,它可以缓解由药物的快速初始释放引起的副作用。

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