124-TRIAZOLO43-aPYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS

摘要

The present invention relates to a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 2 ("mGluR2") of formula I: [Formula I] to a novel 1,2,4-triazolo[4,3-a]pyridine compound of The invention also relates to pharmaceutical compositions comprising such compounds, to methods of making such compounds and compositions, and to the use of such compounds and compositions in the prophylaxis or treatment of disorders of the mGluR2 subtype.