Method for preparing poly(alkyl cyanoacrylate)-based nano/microfiber and use thereof

摘要

The present invention relates to the field of biomaterials, and more particularly to the field of poly(alkyl cyanoacrylate) based nano- and microfibers. The present invention provides a novel process for the preparation of ready-to-use poly(alkyl cyanoacrylate)-based nano/microfibers, which process is produced by anionic polymerization of alkyl cyanoacrylate monomers or oligomers and has a specific polydispersity. electrospinning of poly(alkyl cyanoacrylate) homopolymers or copolymers characterized by a degree index. Accordingly, the present invention also provides novel ready-to-use nano/microfibers obtainable by said method, as well as uses thereof, including wound healing, drug delivery, and (therapeutic) biomedical applications such as tissue regeneration and engineering. do.