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miRNA miRNA marker for diagnosing muscle aging and a diagnostic method using the same

机译:miRNA miRNA标记用于诊断肌肉老化和使用相同的诊断方法

摘要

The present invention relates to a composition, kit, and method for diagnosing muscle aging in an individual by measuring the expression level of a specific miRNA, and a method for diagnosing muscle aging using the same. The two miRNAs (cfa-miR-103 and cfa-let-7a) of the present invention are It was confirmed that the expression level is changed in an individual in an age-dependent manner by ignoring the sample type. The two miRNAs can be used as biomarkers for diagnosing muscle aging, and when using them, invasive biopsy is not required. There are advantages.
机译:本发明涉及一种通过测量特定miRNA的表达水平的组合物,试剂盒和用于诊断肌肉老化的方法,以及使用该方法的诊断肌肉老化的方法。 本发明的两个miRNA(CFA-miR-103和CFA-Let-7a)是证实,通过忽略样品类型以年龄依赖性方式在个体中改变表达水平。 两种miRNA可以用作诊断肌肉老化的生物标志物,并且在使用它们时,不需要侵入性活组织检查。 有优势。

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