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Amyloid Beta Peptide detection sensor in Interdigitated Chain-shaped Electrode

机译:淀粉样蛋白β肽检测传感器在交叉链状电极中

摘要

The present invention relates to an interdigited chain-shped electrode (ICE), wherein the interdigited chain-shped electrode (ICE) includes a substrate, a metal deposited on the substrate surface, and a SAM (self formed on the deposited metal surface). assembly monolayer) and an antibody immobilized at the end of the self assembly monolayer (SAM). According to the present invention, an interdigited chain-shped electrode (ICE) for detecting an amyloid beta peptide, a manufacturing method thereof, and an anti-amyloid beta peptide detection sensor using the same By providing the cerebrospinal fluid (CSF), there is an effect of enabling detection even at 100 pg/ml or less, which is less than the detection limit of anti-amyloid beta peptide of ~500 pg/ml.
机译:本发明涉及一种分叉的链条电极(冰),其中,所述分叉的链条电极(冰)包括衬底,沉积在所述基板表面上的金属,以及所述SAM(在所述沉积的金属表面上形成)。 组装单层)和固定在自组装单层(SAM)的末端固定的抗体。 根据本发明,通过提供脑脊髓液(CSF),将用于检测淀粉样蛋白β肽,其制造方法和抗淀粉样蛋白β肽检测传感器的分支的链条电极(ICE)及其使用相同的抗淀粉样蛋白β肽检测传感器 使得能够在100pg / ml或更小于100pg / ml或更小的效果,其小于〜500pg / ml的抗淀粉样蛋白β肽的检测极限。

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