TLR3 pathway inhibitor, antiinflammatory composition and TLR3 pathway suppressing method

摘要

Problem to be solved: the present invention is a novel type of TLR3 pathway inhibitor, which has excellent inhibitory activity against the signal transduction pathway (TLR3 pathway) from TLR3, is excellent in safety and does not cause any dosing method, and is an anti inflammatory composition comprising the same Problem to be solved is to provide a TLR3 path suppression method using this.The present invention comprisesBacitracinActive vitamin D3FulniolideHalcyonideFluticasone propionateRaloxifene hydrochlorideVinblastine sulfateVinacrine sulfateZafirrukastBinolepinToremenThioodazine hydrochlorideMebendazoleTamoxifen citrateTorakaponEthacrynic acidPiazzideAlbendazoleAcitretinEncataponAtaconBolinostatDoxorubicin hydrochlorideDocetaxelPaclitaxelCarvedilolDino prostonLoratadineTerbinafine hydrochlorideAppressoresExcelsiorTermitartanDanazolMelphalanAnaglyolideTrifluoroperazine hydrochlorideNaistatinPyroxcamBromocriptine mesylateIt is a TLR3 pathway inhibitor containing at least one species selected from the group consisting of cetididine hydrochloride.In the TLR3 pathway inhibitor of the present invention, the active vitamin D3 is preferably calcitotriol.The present invention also includes anti-inflammatory compositions containing TLR3 pathway inhibitors.No selection