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Phosphocofilin: cofilin co-localization intensity as a predictor of metastatic recurrence
Phosphocofilin: cofilin co-localization intensity as a predictor of metastatic recurrence
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机译:磷酸硅蛋白:甲氯蛋白共定位强度作为转移复发的预测
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摘要
Methods and products are provided for determining if a subject having a tumor is at risk of metastasis of the tumor. Specifically, the methods comprise detecting phosphorylated cofilin, and both phosphorylated and non-phosphorylated cofilin; quantifying the phosphorylated cofilin, and the total of phosphorylated and nonphosphorylated cofilin; and determining if a subject having the tumor is likely to experience metastasis of the tumor, based on the ratio of the amount of detected phosphorylated cofilin:total amount of phosphorylated and non-phosphorylated cofilin detected. Further disclosed are the types of tumor metastases that can be determined using the methods provided.
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