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COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DISORDERS ASSOCIATED WITH THE 5-HT1A AND 5-HT2A RECEPTORS

机译:用于治疗与5-HT1A和5-HT2A受体相关的病症的化合物和药物组合物

摘要

Alkyl-piperazine-phenyl 4 (3H)-quinazolinones compounds of general formula (I) below are provided that are pharmacologicaly active and able to act on the 5-HT1A and 5-HT2A serotonin receptors in a manner that promotes the control, relief or cure of disorders associated with these receptors, and pharmaceutical compositions containing the compounds for the treatment of disorders associated with these receptors. These compounds and their pharmaceutical compositions are useful in the treatment of conditions such as depression, anxiety, phobias, addictions, aggressiveness, impulsiveness, panic, psychotic, eating and sleep disorders, obsessive-compulsive disorder and female sexual dysfunctions, including loss of sexual desire, inhibition of sexual desire and absence of sexual desire, among other disorders associated with these receptors.;
机译:提供了下面的通式(I)的烷基 - 哌嗪 - 苯基4(3H) - 喹唑啉酮化合物,其是药理活性,并且能够以促进对照,浮雕或促进所述对照,浮雕 与这些受体相关的病症的固化,以及含有用于治疗与这些受体相关的病症的化合物的药物组合物。 这些化合物及其药物组合物可用于治疗抑郁症,焦虑,噬菌体,瘾,侵略性,冲动,恐慌,精神病,吃胃疾病,痴呆症和女性性功能障碍等条件下有用,包括丧失性欲失去 ,抑制性欲和没有性欲的缺乏,在与这些受体相关的其他疾病中;

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