COMPOSITION FOR PREVENTING OR TREATING ISCHEMIA REPERFUSION INJURY COMPRISING NADPH OXIDASE 1 INHIBITOR AS ACTIVE INGREDIENT

摘要

The present invention relates to a composition for preventing or treating ischemia reperfusion injury, the composition comprising an NADPH oxidase 1 (NOX1) inhibitor as an active ingredient, and more specifically, to a composition exhibiting prophylactic or therapeutic effects on ischemia reperfusion injury by suppressing the signaling of extracellular-signal-regulated kinase (ERK) by means of reactive oxygen species (ROS).